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Sustained-release methylphenidate for cognitive impairment in HIV-1-infected drug abusers: a pilot study

Sustained-release methylphenidate for cognitive impairment in HIV-1-infected drug abusers: a pilot study

Journal of Neuropsychiatry and Clinical Neurosciences 9(1): 29-36

The efficacy of sustained-release methylphenidate (MSR) was examined in a sample of substance abusers with HIV-1-related cognitive impairment. Eight HIV-1-infected methadone patients with impaired neuropsychological test performance participated in an inpatient double-blind placebo-controlled crossover trial of MSR (20 to 40 mg/day). On a composite neuropsychological measure, patients improved significantly from baseline during MSR but not placebo treatment.

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Accession: 002973864

Download citation: RISBibTeXText

PMID: 9017526

DOI: 10.1176/jnp.9.1.29

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