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The cattle major histocompatibility complex (MHC) class-I possesses HLA-like promoters

, : The cattle major histocompatibility complex (MHC) class-I possesses HLA-like promoters. Gene 160(2): 249-252

To study the genetic regulation of the cattle major histocompatibility complex (MHC) class-I, a cattle MHC class-I promoter DNA fragment was isolated and characterized for the first time. Semi-degenerate PCR was performed on cattle genomic DNA and the resulting product was isolated, subcloned and sequenced. Sequence comparison of the HLA-A, -B and -C promoters to the cloned product, designated BL3-6prmtr, revealed the cattle MHC class-I promoter to have close homology to human MHC class-I promoters. To address the ability of the cattle MHC class-I promoter to initiate transcription, BL3-6prmtr was subcloned into a luciferase reporter vector and transiently transfected into cattle and human B-lymphoblastoid cell lines. A strong transcription initiation ability of BL3-6prmtr was observed, including the ability of the enhancer A and interferon response sequence (IRS) to upregulate transcription initiation.

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Accession: 002980039

DOI: 10.1016/0378-1119(95)00051-7

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Alvarez-Sala Walther, J.L.; Urban Poza, M.A.; Fernández Mendieta, F.; Sicilia, J.J.; de Salamanca, E.; Villegas, A., 1978: Sea-blue histiocyte syndrome. Report of a case. Sangre 23(3): 327-333

Nickles, V.B., 1988: The frustration of caring too much. A burnout prevention program for home health caregivers. Caring 7(3): 46-47

Hawkey, C.J., 2000: Risk of ulcer bleeding in patients infected with Helicobacter pylori taking non-steroidal anti-inflammatory drugs. Objective To determine whether Helicobacter pylori is an independent risk factor for bleeding peptic ulcer in users of non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin. Design A prospective matched case-control study. Setting Oden...

LEDERBOGEN.K.; DROSTE.R.; RAUSCH.F., 1960: Serogenetic encephalomyelitis after tetanus vaccination. Deutsches Medizinisches Journal 11: 362-365

Bajaj, Y.P.S.; Collins, W.B., 1967: Effect of some growth regulators on the development of strawberry fruits in vitro. The pollinated and unpollinated flowers of the strawberry variety Sparkle were grown on synthetic media in sterile cultures, and the effects of GA, IBA, NAA, the calyx and light on the development of fruits were studied. In the pollinated flowers,...

Carpentier J.L.; Van Obberghen E.; Gorden P.; Orci L., 1980: Surface re distribution of iodine 125 labeled insulin in cultured human lymphocyte. Diabetologia 19(3): 263

Sane, T.; Tulokas, T.; Nikkanen, P.; Heikkilä, P.; Huttunen, E.; Niskanen, L., 2005: Insulin pump in the treatment of adult age diabetes. Duodecim; Laaketieteellinen Aikakauskirja 121(8): 839-845

Socquet, Y., 1981: Combined surgery and adjuvant chemotherapy with high dose methotrexate and folinic acid rescue (HDMTX-CF) for infiltrating tumours of the bladder. British Journal of Urology 53(5): 439-443

Schuetze G., 1973: Erythrophages in spinal fluid cell diagnosis of subarachnoid bleeding post puncture behavior of erythrocytes and macrophages in cerebro spinal fluid. Nervenarzt: 407-416

Buttaro, D.; Bonasia, A.; Navarro, A.; Serio, F.; Santamaria, P., 2006: Effect of silicon application on carosello and barattiere (Cucumis melo). Carosello and barattiere are types of melon widely grown in Apulia and eaten unripe. In 2005 a trial was conducted in the Bari region to assess the effect on yield, quality and resistance to oidium of introducing silicon at 20 mg/litre into the nu...