EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The cattle major histocompatibility complex (MHC) class-I possesses HLA-like promoters


, : The cattle major histocompatibility complex (MHC) class-I possesses HLA-like promoters. Gene 160(2): 249-252

To study the genetic regulation of the cattle major histocompatibility complex (MHC) class-I, a cattle MHC class-I promoter DNA fragment was isolated and characterized for the first time. Semi-degenerate PCR was performed on cattle genomic DNA and the resulting product was isolated, subcloned and sequenced. Sequence comparison of the HLA-A, -B and -C promoters to the cloned product, designated BL3-6prmtr, revealed the cattle MHC class-I promoter to have close homology to human MHC class-I promoters. To address the ability of the cattle MHC class-I promoter to initiate transcription, BL3-6prmtr was subcloned into a luciferase reporter vector and transiently transfected into cattle and human B-lymphoblastoid cell lines. A strong transcription initiation ability of BL3-6prmtr was observed, including the ability of the enhancer A and interferon response sequence (IRS) to upregulate transcription initiation.

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 002980039

DOI: 10.1016/0378-1119(95)00051-7

Download PDF Full Text: The cattle major histocompatibility complex (MHC) class-I possesses HLA-like promoters


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Platt, J.J.; Buhringer, G.; Kaplan, C.D.; Brown, B.S.; Taube, D.O., 1988: The prospects and limitations of compulsory treatment for drug addiction. Journal of Drug Issues 18(4): 505-525

Cros, Auguste., 1908: Le Trichodes umbellatarum Ol., ses maeurs, son evolution. Bulletin du Museum Paris, 215-221

Haugen, R.K.; Hill, G.E., 1987: A large-scale autologous blood program in a community hospital. A contribution to the community's blood supply. In an attempt to eliminate the hazards of homologous blood transfusions during major orthopedic surgical procedures, 1672 patients donated 6615 units of autologous blood in a ten-year period. Most of the blood components were stored frozen. The au...

Rodilla, F.; Fuentes, M.D.; Chuan, P.; Ferriols, F.; Magraner, J., 1994: Penile self-injection for impotence in patients after radical cystectomy. Four patients with impotence as a result of radical cystectomy were treated with a mixture of papaverine/phentolamine at a 30:1 ratio, with successful results.

FREDERICK.J.N.; KOSMAN.A.J., 1948: Effect of neurotripsy on the partially denervated muscle of the dog. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine 69(3): 605-607

MARTIN NICLOS, J., 1954: The pellet program in pediatrics. Revista Espanola de Pediatria 10(3): 377-394

Yang, C.; Wan, X.; He, Z.; Yang, Q.; Xue, H.; Yu, W., 2011: The choice of null distributions for detecting gene-gene interactions in genome-wide association studies. In genome-wide association studies (GWAS), the number of single-nucleotide polymorphisms (SNPs) typically ranges between 500,000 and 1,000,000. Accordingly, detecting gene-gene interactions in GWAS is computationally challenging because it involve...

Mertz, D.P., 1965: Chronic idiopathic jaundice. On the diagnosis of the Dubin-Johnson syndrome and its borderline conditions. Munchener Medizinische Wochenschrift 107(42): 2041-2048

Cao, X.; Qi, D.; Yin, S.; Bu, J.; Li, F.; Goh, C.Foo.; Zhang, S.; Chen, X., 2013: Ambient fabrication of large-area graphene films via a synchronous reduction and assembly strategy. A synchronous reduction and assembly strategy is designed to fabricate large-area graphene films and patterns with tunable transmittance and conductivity. Through an oxidation-reduction reaction between the metal substrate and graphene oxide, grap...

Wilcox D.H.; Marshall G.; Morrison I.N., 1988: Effect of freezing temperature on the efficacy of wild oat herbicides. In controlled environment experiments diclofop methyl, difenzoquat, flamprop methyl, fluazifop-P and sethoxydim were applied to wild oat at the three-leaf stage at recommended rates 10 h before or after a single night of freezing (-4.degree. C) te...