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Action of a glucocorticoid (prednisolone) on the blood, urine and liver of recently-calved cows

Action of a glucocorticoid (prednisolone) on the blood, urine and liver of recently-calved cows

Tierarztliche Praxis Ausgabe G, Grosstiere/Nutztiere 26(5): 262-268

Prednisolone (200 mg) was injected i.m. into 4 cows once daily for 5 days, starting a week after calving. Samples of blood, urine and liver (biopsy samples) were taken from these cows and from 4 untreated cows, once daily for 5 days. Treatment increased serum glucose and insulin, and decreased free fatty acids, bilirubin, AST activity, GLDH activity and thyroxine; hepatic glycogen increased. There was little change in blood cortisol.

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