+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Alimentary lipemia is enhanced in fiber-fed rats

, : Alimentary lipemia is enhanced in fiber-fed rats. Journal of Nutrition 128(6): 1031-1036

The effect of dietary fiber on the pattern of postprandial lipemia was examined in two studies with male Wistar rats. In the first study, groups of rats were killed after food deprivation (0 h) or 1, 4.5 or 8.5 h after a high fat test meal containing either cellulose (CL) or oat bran (OB). Plasma triglycerides (TG) were higher in the OB group at 4.5 h compared with both the 0-h and the CL-groups at 4.5 h. In both groups, LDL and TG-rich lipoprotein cholesterol (TRL-C) concentrations were higher at 8.5 h than at 0 h; HDL cholesterol was significantly lower at 8.5 h than at 0 h for the OB group only. The enhanced lipemia when OB was fed may stimulate cholesterol movement from HDL to LDL and TRL. To examine, whether TRL secretion rates were responsible for the enhanced lipemia, a second study was conducted. Rats were fitted with jugular catheters and allowed to recover. Two groups were fed either CL or OB and infused with Triton-1339 (400 mg/kg). Two control groups were not fed and were infused with either Triton or saline. Rats were killed 2.5 h after infusion. Plasma TG was 10-fold higher in the Triton group than in the saline group, but did not differ between the OB and CL groups. The relative contribution of TRL-C to total cholesterol was significantly greater in the Triton control than in the OB and CL groups. Enhanced secretion of TRL was not responsible for the lipemia observed in the first study. Rather, alterations in clearance rate were responsible.

Accession: 003035085

PMID: 9614165

Submit PDF Full Text: Here

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Related references

Tall A.; Sammett D., 1985: Mechanisms of enhanced cholesteryl ester transfer during alimentary lipemia. American Heart Association Monograph (114): III-287

Liu G T.; Zhang J T.; Q.Z.W., 1983: Effect of 16 17 pyrazole estrone on alimentary hyper lipemia and athero sclerosis in rats and chickens. In screening new hypocholesterolemic agents, 11 derivatives of estrone were examined in alimentary hyperlipemic rats. Of these, 16,17-pyrazole estrone (16,17-PES) had cholesterol lowering action with weak estrogen activity. S.c. or oral administra...

Tall, A.; Sammett, D.; Granot, E., 1986: Mechanisms of enhanced cholesteryl ester transfer from high density lipoproteins to apolipoprotein B-containing lipoproteins during alimentary lipemia. In vitro lipoprotein lipase enhances the cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters from high density lipoproteins (HDL) to very low density lipoproteins as a result of lipolysis-induced alterations in lipopr...

Wolff, R.; Brignon, J.J., 1961: Research on alimentary lipemia in the rat. Archives Internationales de Pharmacodynamie et de Therapie 130: 75-85

Wolff, R.; Brignon, J.J., 1961: Investigations on the alimentary lipemia in the rat. The opalescence of the plasma, the total amountof lipds and semiquantitatively fractions of lipoproteins are measured. The changes after the ingestion of maize oil, a coconut oil emulsion, lard and fresh cream are described.

Brewster, A.C.; Lankford, H.G.; Schwartz, M.G.; Sullivan, J.F., 1966: Ethanol and alimentary lipemia. Serum triglycerides were estimated in 9 healthy adults before and after a test meal containing 68 or 102 g fat with or without earlier ingestion of 60 ml or 6 oz 85% proof whisky. Significantly higher triglyceride values occurred 3 to 6 h after th...

Barboriak, J.J.; Friedberg, H.D.; Botticelli, J.T., 1971: Propranolol and alimentary lipemia in man. Journal of Laboratory and Clinical Medicine 78(6): 986-986

Barboriak, J.J.; Kory, R.C.; Hamilton, L.H., 1964: Enhancement of alimentary lipemia by heparin. FED PROC 23(2 Pt 1): 145

Spitzer, J.J., 1953: Influence of protamine on alimentary lipemia. Intraven. admn. of protamine to lipemic dogs causes an increase in visible lipemia. The effect can be repeated several times and is an entirely in vivo process. The change after protamine is not due merely to it's anti- heparin nature. 2 othe...

Jochims, J.; Krey, W.D., 1964: On The Age Factor In Alimentary Lipemia In Children. Archiv für Kinderheilkunde 171: 217-229