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Anti-carcinogenic activity of 6-methylsulfinylhexyl isothiocyanate-, an active anti-proliferative principal of wasabi (Eutrema wasabi Maxim.)


Anti-carcinogenic activity of 6-methylsulfinylhexyl isothiocyanate-, an active anti-proliferative principal of wasabi (Eutrema wasabi Maxim.)



Cytotechnology 25(1-3): 197-203



ISSN/ISBN: 0920-9069

PMID: 22358892

DOI: 10.1023/a:1007918508115

Synthetic 4-methylsulfinylhexyl isothiocyanate (MITC) (a potent inducer of phase 2 detoxification enzymes from broccoli) and 6-MITC (a potent anti-proliferative principal from E. wasabi) slightly inhibited the induction of mouse skin tumours in a 2-stage process of carcinogenesis (initiator, 9,10-dimethyl-1,2-benzanthracene; promoter, 12-O-tetradecanoylphorbol-13-acetate), but the effect was not significant.

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Accession: 003042541

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