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Chagas' disease and the autoimmunity hypothesis

Chagas' disease and the autoimmunity hypothesis

Clinical Microbiology Reviews 12(2): 210-223

This review covers: Trypanosoma cruzi and molecular mimicry; antibodies to host tissue antigens; antibodies to functional target molecules; polyclonal activation and autoantibody formation;; cellular aspects of autoimmunity; are parasites really absent at chronic chagasic tissue lesions?; nonautoimmune hypotheses for the production of chronic chagasic tissue lesions.

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Accession: 003061637

Download citation: RISBibTeXText

PMID: 10194457

DOI: 10.1128/cmr.12.2.210

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