+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Determination of sulfonic acid degradates of chloroacetanilide and chloroacetamide herbicides in groundwater by LC/MS/MS



Determination of sulfonic acid degradates of chloroacetanilide and chloroacetamide herbicides in groundwater by LC/MS/MS



Analytical Chemistry Washington 70(13): 2699-2703



An analytical method is presented which permits qualitative and quantitative analysis of sulfonic acid degradates of three chloroacetanilide herbicides (acetochlor, alachlor, and metolachlor) and one chloroacetamide herbicide (dimethenamid) in groundwater at trace levels with determination by LC/MS/MS. The analytes were isolated from groundwater by solid-phase extraction (SPE). The final samples were analyzed by reversed-phase HPLC with MS/MS detection utilizing a pneumatically assisted, and heat-assisted electrospray interface (TurboIonSpray). Unique precursor/production pairs were obtained in the MS/MS mode which permitted conclusive identification of each analyte, even when the analytes coeluted. Quantification was performed by generation of an external calibration curve. Excellent linearity was obtained over a calibration range from 0.25 to 10 ng injected on-column, with all linear correlation coefficients exceeding 0.999. Method performance for this analytical procedure was validated by analyzing groundwater samples fortified at levels of 0.1, 1, and 50 ppb. The average recovery at each fortification level for each analyte exceeded 89%. Excellent method precision was demonstrated with percent relative standard deviations of less than 10% for all analytes at all fortification levels.

(PDF emailed within 0-6 h: $19.90)

Accession: 003090535

Download citation: RISBibTeXText

PMID: 9666733

DOI: 10.1021/ac971365d


Related references

Determination of chloroacetanilide and chloroacetamide herbicides and their polar degradation products in water by LC/MS/MS. Abstracts of Papers American Chemical Society 223(1-2): ENVR 8, 2002

Nuclear magnetic resonance identification of new sulfonic acid metabolites of chloroacetanilide herbicides. Journal of Agricultural & Food Chemistry 45(4): 1240-1243, 1997

Analysis and detection of the herbicides dimethenamid and flufenacet and their sulfonic and oxanilic acid degradates in natural water. Journal of agricultural and food chemistry, 50(5): 1045-1052, 2002

Degradation of chloroacetanilide herbicides: the prevalence of sulfonic and oxanilic acid metabolites in Iowa groundwaters and surface waters. Environmental Science and Technology 32(11): 1738-1740, 1998

Neutral Degradates of Chloroacetamide Herbicides: Occurrence in Drinking Water and Removal During Conventional Water Treatment. Water Research 42(20): 0-4914, 2008

Development of EPA method 535 for the determination of chloroacetanilide and other acetamide herbicide degradates in drinking water by solid-phase extraction and liquid chromatography. Journal of AOAC International 89(1): 201-209, 2006

Occurrence of herbicides and their degradates in Hawaii's groundwater. Bulletin of Environmental Contamination and Toxicology 66(5): 653-659, 2001

Analysis of neutral chloroacetamide degradates in water via GC/MS. Abstracts of Papers American Chemical Society 226(1-2): AGRO 22, 2003

Gas chromatographic determination of chloroacetamide herbicides in plants and soil. Journal of Chromatography 455: 391-395, 1988

Are neutral chloroacetamide herbicide degradates of potential environmental concern? Analysis and occurrence in the upper Chesapeake Bay. Environmental Science and Technology 39(17): 6561-6574, 2005

Removal of neutral chloroacetamide herbicide degradates during simulated unit processes for drinking water treatment. Water Research 39(20): 5033-5044, 2005

Acid- and base-catalyzed hydrolysis of chloroacetamide herbicides. Journal of Agricultural and Food Chemistry 54(13): 4740-4750, 2006

Neutral chloroacetamide herbicide degradates and related compounds in Midwestern United States drinking water sources. Science of the Total Environment 390(1): 155-165, 2007

Herbicides and herbicide degradates in shallow groundwater and the Cedar River near a municipal well field, Cedar Rapids, Iowa. Science of the Total Environment 248(2/3): 241-253, 2000

Determination of the chloroacetanilide herbicides in waters using single-drop microextraction and gas chromatography. Microchemical Journal 83(2): 105-110, 2006