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Efficacy of ivermectin in a controlled-release capsule for the control of breech strike in sheep

, : Efficacy of ivermectin in a controlled-release capsule for the control of breech strike in sheep. Australian Veterinary Journal 76(5): 350-354, May

Objective: To investigate the efficacy of ivermectin in an intraruminal controlled-release capsule (CRC) against blowfly strike. Design: Pen and field trials with controls. Animals: Pen studies: Two breech strike trials involving 60 Romney and 60 Merino sheep. One body strike trial using 100 Merino sheep. Field trials: Eight trials in New Zealand used 1000 Romney and Romney-cross sheep. Fifty Merino lambs in one trial in Australia. Procedure: Pen studies: Sheep were allocated to two equal groups. One was not treated, the other sheep received a CRC that delivered ivermectin at gtoreq 20 mug/kg/day for 100 days. In the breech strike trials, each animal was given an oral laxative 2 days before exposure to adult Lucilia cuprina. In the body-strike trial, the sheep were kept wet to increase susceptibility prior to the release of blowflies. Field trials: Fifty or 200 sheep allocated to equal groups of nontreated or treated with the CRC and grazed at pasture exposed to natural blowfly challenge. Results: Pen studies: Breech strikes developed in 24 of 60 controls but in none of 60 CRC-treated sheep. There was a 35% reduction in the number of CRC-treated sheep struck on the body. Field trials: The average number of breech strikes in CRC-treated sheep was reduced by 86% (P < 0.001). The number of body strikes in the treated groups was a reduced by 27% (P < 0.05). Conclusion: The ivermectin CRC is a useful aid in controlling breech strike, but provides only moderate reduction in the incidence of body strike.

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Accession: 003122896

PMID: 9631706

DOI: 10.1111/j.1751-0813.1998.tb12366.x

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