Evaluation of estradiol hormone profile of ewes during early pregnancy, preterm and early lactation

Rodrigues, P.A.; Vicente, W.R.R.; Cipolla Neto, J.; Oliveira, C.A. de

Ars Veterinaria 14(2): 156-164

1998


Accession: 003131734

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Abstract
To determine the physiological patterns of oestradiol in pregnant and lactating ewes, and to verify whether hormone secretion showed 24-h rhythms, blood samples were obtained every 4 h for 24 h from 15 ewes at a research facility in Jaboticabal (Brazil) during early pregnancy, late pregnancy and early lactation. Hormone concentration was measured by radioimmunoassay and the circadian rhythm by cosinor analyses and autocorrelation. At the beginning of gestation serum oestradiol concentrations were low (2.8 pg/ml), concentrations had increased significantly (P<0.05) at 7 and 2 days before parturition (20.48 and 46.12 pg/ml respectively). Autocorrelation analysis showed that this hormone had a circadian rhythm that was more evident during late gestation, than during early pregnancy and lactation.