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Fed-batch fermentation to produce oligonucleotides from Kluyveromyces marxianus grown on whey

Fed-batch fermentation to produce oligonucleotides from Kluyveromyces marxianus grown on whey

Process Biochemistry 34(5): 501-509

Oligonucleotides (ON) extracted from yeasts are used as antiviral agents, immunostimulators, and flavour enhancers. Fed-batch fermentation of whey by Kluyveromyces marxianus was carried out to produce high biomass yields to extract ON. K. marxianus was grown for 20 h in medium containing 5% (w/v) dried whey, at 30 degrees C (pH 4.5), with agitation (350 rpm), and under aeration (1.0-2.0 vvm).

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Accession: 003139813

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DOI: 10.1016/s0032-9592(98)00118-6

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