Section 4
Chapter 3,158

H-2M molecules, like MHC class II molecules, are targeted to parasitophorous vacuoles of Leishmania-infected macrophages and internalized by amastigotes of L. amazonensis and L. mexicana

Antoine, J.C.; Lang, T.; Prina, E.; Courret, N.; Hellio, R.

Journal of Cell Science 112: 2559-2570


ISSN/ISBN: 0021-9533
PMID: 10393812
Accession: 003157423

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The fate of the MHC molecule H-2M, an essential cofactor for some major histocompatibility complex (MHC) class II antibodies, in mouse macrophages infected with Leishmania amastigotes was studied. H-2M was detected in the parasitophorous vacuoles (PV) of macrophages infected with various Leishmania species including L. amazonensis, L. mexicana, L. major and L. donovani.

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