EurekaMag.com logo
+ Translate

Hormonal profiles of callipyge and normal sheep


, : Hormonal profiles of callipyge and normal sheep. Journal of Animal Science 76(5): 1443-1447

Five sheep expressing the callipyge gene, which causes muscle hypertrophy, were compared with five normal sheep to determine whether endocrine differences existed between genotypes. Blood samples were taken at 15-min intervals for 6 h to measure serum concentrations of growth hormone and insulin. Thyroxine and IGF-I levels were determined in single samples. No differences were found in mean serum growth hormone concentrations, growth hormone pulse amplitude, or pulse frequency (P > .3). Insulin concentrations were not different between genotypes before or after feeding (4.5 +/- 1.3 ng/mL callipyge vs 4.9 +/- 1.7 ng/mL normal, P > .4). The IGF-I concentrations did not differ (273.8 +/- 17.6 ng/mL callipyge vs 261.4 +/- 12.3 ng/mL normal). Serum thyroxine concentrations also were not different (5.9 +/- 2.3 microg/mL for callipyge vs 5.1 +/- 2.1 microg/mL normal, P > .3). In a separate experiment, five ewe lambs with and five without the callipyge gene were stressed to determine whether the adrenocortical response to stress differed between genotypes. Blood samples were taken at 15-min intervals for 2 h before, during, and after restraint stress. Restraint increased serum cortisol concentrations in both groups (P < .001), but genotypes did not differ at any time (P > .3). These results suggest that differences in muscling are not due to differences in systemic hormone secretion. The results of the second experiment indicate that callipyge and normal sheep have similar adrenocortical responses to stress.

(PDF 0-2 workdays service)

Accession: 003161720

PMID: 9621952

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

Kline, R.S.; Whisnant, C.S.; Zaunbrecher, G.M.; Branum, J.C.; Jackson, S.P., 1995: Comparison of hormonal patterns in callipyge and normal sheep. Journal of Animal Science 73(SUPPL 1): 137

Busboom, J.R.; Hendrix, W.F.; Gaskins, C.T.; Cronrath, J.D.; Jeremiah, L.E.; Gibson, L.L., 1994: Cutability fatty acid profiles and palatability of callipyge and normal lambs. Journal of Dairy Science 77(SUPPL 1): 61

Delgado, E.F.; Geesink, G.H.; Marchello, J.A.; Goll, D.E.; Koohmaraie, M., 2001: The calpain system in three muscles of normal and callipyge sheep. Activities of mu- and m-calpain and of calpastatin were measured at four different times during postmortem storage (0, 1, 3, and 10 d) in three muscles from either callipyge or noncallipyge (normal) sheep. The weights of two muscles, the biceps fe...

Bidwell, C.A.; Kramer, L.N.; Perkins, A.C.; Hadfield, T.S.; Moody, D.E.; Cockett, N.E., 2004: Expression of PEG11 and PEG11AS transcripts in normal and callipyge sheep. The callipyge mutation is located within an imprinted gene cluster on ovine chromosome 18. The callipyge trait exhibits polar overdominant inheritance due to the fact that only heterozygotes inheriting a mutant paternal allele (paternal heterozygo...

Kline, R.S.; Whisnant, C.S., 1994: Insulin-like growth factor-I binding in muscles from callipyge and normal sheep. Journal of Dairy Science 77(SUPPL 1): 60

A.H.ssan, M.J.; Roberts, A.J., 1995: Serum insulin-like growth factor I and IGF binding proteins in Callipyge and normal sheep. Journal of Animal Science 73(SUPPL 1): 87

Hossner, K.L.; Yemm, R.S.; Bernal Santos, G.; Snowder, G.D.; Johnson, D.E., 1995: Alteration of the insulin and insulin-like growth factor I system in response to nutrient restriction in callipyge and non-callipyge sheep. Journal of Animal Science 73(SUPPL 1): 138

Delgado, E.F.; Geesink, G.H.; Marchello, J.A.; Goll, D.E.; Koohmaraie, M., 2001: Properties of myofibril-bound calpain activity in longissimus muscle of callipyge and normal sheep. Properties of the calpain bound to myofibrils in longissimus muscle from callipyge or noncallipyge sheep were examined after 0, 1, 3, and 10 d of postmortem storage at 4 degrees C. Western analysis has shown that most of this calpain is mu-calpain...

Singh N.; Gangwar P.C., 1991: Hormonal profiles in normal and anestrus buffaloes during summer. Indian Veterinary Journal 68(10): 993-994

Cockett, N.E.; Berghams, S.; Beckers, M.C.; Shay, T.L.; Jackson, S.P.; Snowder, G.D.; Georges, M., 1997: The callipyge gene of sheep. The callipyge locus is characterized by a novel form of nonmendelian inheritance, referred to as polar overdominance. Acquiring a molecular understanding of this novel biological phenomenon will contribute to the understanding of complex traits, i...