+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Human monoclonal antibodies to the V3 loop of HIV-1 with intra- and interclade cross-reactivity

Human monoclonal antibodies to the V3 loop of HIV-1 with intra- and interclade cross-reactivity

Journal of Immunology 159(10): 5114-5122

Five human anti-V3 monoclonal antibodies (mAbs) were generated from Ab-producing cells derived from the blood of HIV-1-infected individuals from North America and selected using the V3 peptide of a divergent clade B isolate, HIVRF. The anti-V3RF mAbs were mapped to a cluster of 3 overlapping epitopes present in the KSITKGP sequence located in the hypervariable region on the N-terminal side of the V3 loop.

(PDF 0-2 workdays service: $29.90)

Accession: 003162995

Download citation: RISBibTeXText

PMID: 9366441

Related references

Relation between cross reactivity and affinity of human monoclonal antibodies humabs to synthetic peptides of the v3 loop of divergent hiv strains. Istituto Superiore Di Sanita Vii International Conference on Aids: Science Challenging Aids; Florence, Italy, June 16-21, 464p (Vol 1); 460p (Vol 2) Istituto Superiore Di Sanita: Rome, Italy Paper : 171, 1991

A human immunodeficiency virus prime-boost immunization regimen in humans induces antibodies that show interclade cross-reactivity and neutralize several X4-, R5-, and dualtropic clade B and C primary isolates. Journal of Virology 74(21): 10025-10033, 2000

Monoclonal antibodies reactive with human T cell lymphotropic virusI (HTLVI) p19 internal core protein: cross-reactivity with normal tissues and differential reactivity with HTLV types I and II. Journal of Immunology 135(1): 247-254, 1985

Type specific human monoclonal antibodies cross react with the v3 loop of various hiv 1 isolates. Brown, F , Et Al (Ed ) Vaccines (Cold Spring Harbor), 92 Modern Approaches to New Vaccines Including Prevention Of Aids; Ninth Annual Meeting, Cold Spring Harbor, New York, Usa, September 19-23, 1991 Xxiii+408p Cold Spring Harbor Laboratory Press: Plainview, New York, Usa Illus Paper 171-174, 1992

Cross-reactivity of 75 monoclonal antibodies to human immunoglobulin with sera of non-human primates. Immunology Letters. 37(2-3): 207-213, 1993

Cross reactivity of anti-human CD monoclonal antibodies with porcine leukocytes. Veterinary Immunology & Immunopathology 54(1-4): 113, 1996

Cross-reactivity of anti-human monoclonal antibodies with animal leukocytes. FASEB Journal 10(6): A1196, 1996

Interspecies cross-reactivity of monoclonal antibodies to various epitopes of human plasminogen. Archives of Biochemistry and Biophysics 230(1): 306-315, 1984

Monoclonal antibodies against lipopolysaccharide of Chlamydia trachomatis with cross reactivity to human ApoB. Hybridoma 30(2): 131-136, 2011

Cross reactivity of anti lymphocyte monoclonal antibodies on human skin components. Reinherz, E L Et Al (Ed ) Leukocyte Typing Ii, Vol 1 Human T Lymphocytes; 2nd International Workshop on Human Leukocyte Differentiation Antigens, Boston, Mass , Usa, Sept 17-20, 1984 Xx+549p Springer-Verlag: New York, N Y , Usa; Berlin, West Germany Illus 406-414, 1986

Cross reactivity of human brain tumors with lymphoid associated and hematopoietic associated monoclonal antibodies. Journal Of Neuroimmunology: 177, 1985

Monoclonal antibodies raised against the e7 orf of hpv18 cross reactivity with human cellular components. Journal of Cellular Biochemistry Supplement (13 PART C): 213, 1989

Monoclonal antibodies to cobra venom a factor cross reactivity with human complement c 3. Complement 2(1): 30, 1985

Interspecies cross-reactivity of monoclonal antibodies directed against human sperm antigens. Biology of Reproduction 30(4): 1015-1026, 1984

Monoclonal antibodies demonstrating cross reactivity between group a streptococci and human skin. Journal of Investigative Dermatology 84(4): 297, 1985