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A short period of maternal nutrient restriction in late gestation modifies pituitary-adrenal function in adult guinea pig offspring



A short period of maternal nutrient restriction in late gestation modifies pituitary-adrenal function in adult guinea pig offspring



Neuroendocrinology 73(5): 302-311



Altered fetal environment can program the hypophyseal-pituitary-adrenal (HPA) axis development and thus affect endocrine function in later life. We hypothesized that 48 hours of maternal nutrient restriction, during the period of maximal fetal brain growth alters HPA function in adult offspring and leads to modified blood pressure regulation.

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Accession: 003347759

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PMID: 11399903

DOI: 54647



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