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Airway remodeling is absent in CCR1-/- mice during chronic fungal allergic airway disease

Airway remodeling is absent in CCR1-/- mice during chronic fungal allergic airway disease

Journal of Immunology 165(3): 1564-1572

Since lung concentrations of macrophage inflammatory protein-1 alpha and RANTES were significantly elevated after A. fumigatus-sensitized mice received an intrapulmonary challenge with A. fumigatus spores or conidia, this study investigated the role of their receptor, C-C chemokine receptor 1 (CCR1), in this model.

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Accession: 003354471

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PMID: 10903765

DOI: 10.4049/jimmunol.165.3.1564

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