Section 4
Chapter 3,375

CXC chemokine receptor-2 ligands are necessary components of neutrophil-mediated host defense in invasive pulmonary aspergillosis

Mehrad, B.; Strieter, R.M.; Moore, T.A.; Tsai, W.C.; Lira, S.A.; Standiford, T.J.

Journal of Immunology 163(11): 6086-6094


ISSN/ISBN: 0022-1767
PMID: 10570298
Accession: 003374412

Whether the interaction of ELR+ CXC chemokines with CXC chemokine receptor-2 (CXCR2), their sole murine receptor, is a major component of neutrophil-dependent pulmonary host defence against Aspergillus fumigatus was investigated. In immunocompetent animals, neutrophils were recruited to the lung in response to intratracheally administered A. fumigatus conidia.

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