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Comparison of the pathogenicity in rats of rat coronaviruses of different neutralization groups



Comparison of the pathogenicity in rats of rat coronaviruses of different neutralization groups



Laboratory Animal Science 49(5): 514-518



The aim of this study was to determine whether antigenically different strains of coronaviruses (RCVs) vary in their pathogenic potential in rats. Neutralization groups were identified using RCV strain-specific antisera. Sprague Dawley rats were inoculated oronasally with RCV-SDA, RCV-BCMM, or RCV-W. Three groups of 8 experimentally infected rats and a single control group of 2 uninfected rats were studied.

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Accession: 003389596

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PMID: 10551452


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