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Cross-reactivity studies of a new group 2 allergen from the dust mite Glycyphagus domesticus, Gly d 2, and group 2 allergens from Dermatophagoides pteronyssinus, Lepidoglyphus destructor, and Tyrophagus putrescentiae with recombinant allergens



Cross-reactivity studies of a new group 2 allergen from the dust mite Glycyphagus domesticus, Gly d 2, and group 2 allergens from Dermatophagoides pteronyssinus, Lepidoglyphus destructor, and Tyrophagus putrescentiae with recombinant allergens



Journal of Allergy and Clinical Immunology 107(3): 511-518



G. domesticus messenger RNA was isolated from 1 g of living mites. An N-terminal amino acid sequence was obtained from an IgE-binding protein of approximately 15 kd in G. domesticus extract: GKMNFKDXGKGEVKEVKELDI. Two different polymerase chain reaction clones were, sequenced, and identified as group 2 allergens and were named Gly d 2.01 and Gly d 2.02 (designated Gly 2; inhibits IgE binding to native Gly d 2 in G. domesticus extract).

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Accession: 003395603

Download citation: RISBibTeXText

PMID: 11240953

DOI: 10.1067/mai.2001.112264


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