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Different degrees of dietary iron repletion on the hepatic iron activities and regulatory proteins in iron deficiency anemic rats



Different degrees of dietary iron repletion on the hepatic iron activities and regulatory proteins in iron deficiency anemic rats



Nutritional Sciences Journal 25(1): 17-28



Iron regulatory proteins (IRPs) are the key regulators in cellular iron homeostasis. Dietary iron deficiency rapidly increases the spontaneous activity of IRPs and reduces hepatic content of ferritin and mitochondrial aconitase (m-Acon). This study evaluated the interrelationship between hemoglobin, hepatic IRPs activity and ferritin and m-Acon content during recovery from iron deficiency anemia using a series of dietary iron supplementation in a rat model.

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Accession: 003406722

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