EurekaMag.com logo
+ Site Statistics
References:
47,893,527
Abstracts:
28,296,643
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Disposition kinetics of ofloxacin in Black Bengal goats following single oral administration


, : Disposition kinetics of ofloxacin in Black Bengal goats following single oral administration. Indian Journal of Animal Health 39(2): 56-60

The pharmacokinetic values of ofloxacin were studied in 6 Black Bengal lactating goats following single oral administration at 20 mg/kg body weight. (Calcutta, India; date not given). Ofloxacin concentrations in plasma were determined by a 2-compartment open model. The drug was detected at 0.75 h, maximum at 2 h and minimum at 7 h, in plasma following oral administration of the drug. Elimination half life was 1.6+or-0.12 h.


Accession: 003408538

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

Mandal, T.K.; Chakraborty, A.K.; Bhattacharya, A.; Ghosh, R.K.; Majumder, S., 1996: The disposition kinetics and residues of fenvalerate in tissues following a single dermal application to black Bengal goats. The disposition kinetics of fenvalerate were studied in goats after dermal application of 100 ml of 0.25% (w/v) solution. The insecticide persisted in the blood for 72 h. The mean (+/- SEM) Vd(area) and apparent t 1/2 (beta) were 9.92 +/- 1.44 L/k...

Mandal, T.K.; Chakraborty, A.K.; Bhattacharya, A.; Ghosh, R.K.; Majumder, S., 1996: The disposition kinetics and residues of fenvalerate in tissues following a single dermal application to black Bengal goats. The disposition kinetics of fenvalerate were studied in goats after dermal application of 100 ml of 0.25% (w/v) solution. The insecticide persisted in the blood for 72 h. The mean (+/- SEM) Vd(area) and apparent t 1/2 (beta) were 9.92 +/- 1.44 L/k...

Mandal, T.K.; Chakraborty, A.K.; Anjan Bhattacharyya, 2000: Disposition kinetics and residues of cypermethrin in tissues after single dermal application to black Bengal goats. The kinetics of cypermethrin were studied in goats after a single dermal application of 100 ml of 0.25% (w/v) solution. The insecticide persisted in the blood for 96 h. The adrenal gland contained the highest concentration, followed by the heart,...

Mandal, T.K.; Chakraborty, A.K.; Bhattacharya, A.; Ghosh, R.K.; Majumder, S., 1996: The disposition kinetics and residue of fenvalerate in tissues following a single dermal application to Black Bengal goats. After dermal application of 100 ml of 0.25% (w/v) solution, fenvalerate persisted in the blood for 72 h. The mean (+or- SEM) Vd(area) and apparent t0.5 ( beta ) were 9.92 +or- 1.44 litres/kg and 17.51 +or- 2.65 h. The AUC and ClB values were 82.15...

Mallick, T.K.; Sardar, K.K.; Parija, S.C.; Patel, M.B.; Mishra, S.N., 1997: Disposition kinetics of diminazene in Black Bengal goats. Indian Journal of Animal Sciences 67(11): 976-977, Nov

Mandal, T.K.; Chakraborty, A.K.; Bhattacharyya, A., 1995: Disposition kinetics of cypermethrin and fenvalerate in Black Bengal lactating goats. Disposition kinetics of cypermethrin and fenvalerate were investigated in lactating black Bengal goats following single dose intravenous administration at 57 and 45 mg kg-1 respectively. The maximum and minimum blood concentrations of cypermethrin...

Gaur, A.; Garg, S.K.; Saini, S.P.S., 2005: Comparative disposition kinetics of ofloxacin following a single i.m. and s.c. administration in neonatal calves. This study was conducted to determine the pharmacokinetics of ofloxacin following single i.m. (intramuscular) and s.c. (subcutaneous) injections in neonatal calves and to suggest a rational dosage regimen of this antimicrobial agent for its safe a...

Juliet, S.; Chakraborty, A.K.; Koley, K.M.; Mandal, T.K.; Bhattacharyya, A., 2001: Toxico-kinetics, recovery efficiency and microsomal changes following administration of deltamethrin to black Bengal goats. A study of the toxico-kinetics, recovery percentage from different substrates, cytotoxicity and role of cytochrome P450 and b5 of liver microsome in the metabolism of deltamethrin were carried out in female black Bengal goat. The ALD50 value of de...

Sinha, M.; Prasad, R.; Pandey, S.N.; Singh, K.K.; Roy, B.K., 2007: Milk excretion of ofloxacin after single intravenous and oral administration in healthy and febrile goats. A study on the excretion of ofloxacin (Tarivid, 20 mg/kg orally) was conducted in healthy and febrile Black Bengal goats. Ofloxacin diffused passively through mammary gland and milk drug concentrations were found to be adequate to combat bacterial...

Nawaz, M.; Tabassum, R.; Iqbal, T.; Perveen, Z., 1990: Disposition kinetics, renal clearance and excretion of ampicillin after oral administration in goats. Disposition kinetics, renal clearance and urinary excretion of ampicillin were determined after oral administration of 10 mg/kg in 8 goats. Peak plasma concentration 1.86 .+-. 0.14 .mu.mol/l was attained at 117 .+-. 11 min after oral administratio...