EurekaMag.com logo
+ Site Statistics
References:
47,893,527
Abstracts:
28,296,643
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Distinct humoral and cellular immune response to an immunogenic caprine arthritis encephalitis virus p25-Gag peptide in homozygous goats of different MHC-haplotypes


, : Distinct humoral and cellular immune response to an immunogenic caprine arthritis encephalitis virus p25-Gag peptide in homozygous goats of different MHC-haplotypes. Archiv fur Tierzucht 42(Special issue): 133-137

An association of the caprine class I MHC antigen Be1 marked haplotype and onset of caprine arthritis (CAE) has previously been demonstrated. In this experiment, Be1-D5 haplotype carriers as well as goats expressing an non disease-associated haplotype Be10-D2 were backcrossed in order to explore potential differences in their respective immune responses. Six homozygous animals per group were immunized with a synthetic peptide containing a B- and T- cell epitope.


Accession: 003408785

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

Cheevers, W.P.; Hotzel, I.; Beyer, J.C.; Kumpula McWhirter, N., 2000: Immune response to caprine arthritis-encephalitis virus surface protein induced by coimmunization with recombinant vaccinia viruses expressing the caprine arthritis-encephalitis virus envelope gene and caprine interleukin-12. The objective of this study was to determine if interleukin (IL)-12 can focus an antigen specific type 1 immune response characterized by activation of Th 1 lymphocytes and production of IgG2 antibodies in vivo. Saanen goats co-immunized with reco...

Johnson, G.C.; Barbet, A.F.; Klevjer-Anderson, P.; McGuire, T.C., 1983: Preferential immune response to virion surface glycoproteins by caprine arthritis-encephalitis virus-infected goats. Six months after inoculation with caprine arthritis-encephalitis virus, the serum and synovial fluid of virus-infected goats had antibodies to [35S]methionine-labeled viral proteins with apparent molecular weights of 125,000, 90,000, 28,000, and 1...

Ding, E.Y.; Xiang, W.H., 1997: Immune responses in goats to caprine arthritis-encephalitis virus. In this study, goats were experimentally infected with caprine arthritis-encephalitis virus (CAEV). Anti-CAEV antibodies were detected in vivo using indirect enzyme-linked immunosorbent assay (ELISA) and Western blot assays. The results showed tha...

Adams, D.S.; Crawford, T.B.; Banks, K.L.; McGuire, T.C.; Perryman, L.E., 1980: Immune responses of goats persistently infected with caprine arthritis-encephalitis virus. Eight cesarean-derived goat kids were inoculated with caprine arthritis-encephalitis virus (CAEV), and proliferative responses of their peripheral blood mononuclear cells to mitogens and CAEV antigen were monitored for 9 months. Antibody specific...

Zink, M.C.; Yager, J.A.; Myers, J.D., 1990: Pathogenesis of caprine arthritis encephalitis virus. Cellular localization of viral transcripts in tissues of infected goats. Pathologic specimens of 18 goats with classical lesions of caprine arthritis-encephalitis (CAE) virus infection were examined morphologically and by in situ hybridization using molecularly cloned CAEV deoxyribonucleic acid (DNA) to determine which...

Klevjer-Anderson, P.; McGuire, T.C., 1982: Neutralizing antibody response of rabbits and goats to caprine arthritis-encephalitis virus. Rabbits were immunized with purified caprine arthritis-encephalitis virus and examined for neutralizing activity. Analysis of virus-antiserum interaction at 37 degrees C demonstrated little loss of viral infectivity after incubation with heat-inac...

Pimentel Smith, G.E.; Phadtare, J.; Reddy, P.G.; Adeyemo, O., 1993: Analysis of antibody response to caprine arthritis encephalitis virus infection in goats. Journal of Immunology 150(8 PART 2): 235A

McGuire, T.C., 1987: The immune response to viral antigens as a determinant of arthritis in caprine arthritis-encephalitis virus infection. Evidence is reviewed which indicates that CAEV persists in infected goats with variable and restricted expression. Immunosuppression prevents the lesions caused by CAEV. Arthritis is enhanced in CAEV-challenged goats that have been immunized with...

Adebayo, I.A.; Awoniyi, T.A.M., 2004: Immunological response of West-Africa dwarf goats to Caprine Arthritis Encephalitis Virus infection. This study was conducted to investigate the immunological response of West African Dwarf goats (n=117) suspected of caprine arthritis encephalitis virus (CAEV) infection over a 10-month period. Employing the sodium dodecyl sulfate-polyacrylamide g...

Adebayo, I.Abayomi.; Walbey, D.; Adeyemo, O., 2003: Host differences in serum antibody response during infection of goats by caprine arthritis-encephalitis virus. The response of goats infected with caprine arthritis encephalitis virus was evaluated by estimating the binding antibodies in serum. The immunoreactive proteins of the CAEV, strain 63, were determined by immunobloting the lysate against the serum...