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Drug resistance in P. falciparum in the urban environment in Yaounde, Cameroon. Part 2: evaluation of the efficacy of amodiaquine and of the combination sulfadoxine-pyrimethamine for the treatment of simple Plasmodium falciparum malaria in Yaounde, Cameroon



Drug resistance in P. falciparum in the urban environment in Yaounde, Cameroon. Part 2: evaluation of the efficacy of amodiaquine and of the combination sulfadoxine-pyrimethamine for the treatment of simple Plasmodium falciparum malaria in Yaounde, Cameroon



Tropical Medicine and International Health 5(9): 620-627



The spread of chloroquine resistance or its stabilization at a high level calls for a change in the therapeutic strategy, including a possible replacement of chloroquine. We assessed and compared the efficacy of amodiaquine and sulfadoxine-pyrimethamine in Yaounde. Of 140 adults and children >5 years enrolled in the study, 59 in the amodiaquine and 58 in the sulfadoxine-pyrimethamine treatment group were followed until day 14.

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