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Effect of genetic modifications by selection for immunological tolerance on fungus infection in mice

Effect of genetic modifications by selection for immunological tolerance on fungus infection in mice

Microbes and Infection 3(3): 215-222

ISSN/ISBN: 1286-4579

PMID: 11358715

DOI: 10.1016/s1286-4579(01)01373-9

Two strains of mice genetically selected for extreme phenotypes of immunological tolerance to ovalbumin, susceptible (TS) and resistant (TR), were experimentally infected with Sporothrix schenckii. The objective was to observe whether the genetic modifications produced by the selection might be associated with interstrain differences in adaptive immune and innate responses to infection.

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Accession: 003417845

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