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Efficacies of free and liposome-encapsulated enrofloxacin (BaytrilReg.) against Staphylococcus aureus infection in Turkish Shepherd Dog neutrophils in vitro

Efficacies of free and liposome-encapsulated enrofloxacin (BaytrilReg.) against Staphylococcus aureus infection in Turkish Shepherd Dog neutrophils in vitro

Revue de Medecine Veterinaire 151(5): 415-420

The influence of free and liposome-encapsulated enrofloxacin at concentrations of 1, 2 and 4 micro g/ml was studied on phagocytic and intracellular killing of Staphylococcus aureus, in cultured neutrophils of six healthy Turkish Shepherd Dogs. Enrofloxacin was encapsulated by using reverse-phase evaporation method in multilamellar liposomes composed of 15 mg egg phosphatidylcholine and 35 mg cholesterol.

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