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Folding of the group I intron ribozyme from the 26S rRNA gene of Candida albicans



Folding of the group I intron ribozyme from the 26S rRNA gene of Candida albicans



Nucleic Acids Research 29(12): 2644-2653



Preincubation of the group I intron Ca.LSU from Candida albicans at 37 degrees C in the absence of divalent cations results in partial folding of this intron. This is indicated by increased resistance to T1 ribonuclease cleavage of many G residues in most local helices, including P4-P6, as well as the non-local helix P7, where the G binding site is located.

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Accession: 003449178

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PMID: 11410674

DOI: 10.1093/nar/29.12.2644


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