Section 4
Chapter 3,465

Histone H4 acetylation of euchromatin and heterochromatin is cell cycle dependent and correlated with replication rather than with transcription

Jasencakova, Z.; Meister, A.; Walter, J.; Turner, B.M.; Schubert, I.

Plant Cell 12(11): 2087-2100


ISSN/ISBN: 1040-4651
PMID: 11090211
DOI: 10.1105/tpc.12.11.2087
Accession: 003464061

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Reversible acetylation of nucleosomal histones H3 and H4 generally is believed to be correlated with potential transcriptional activity of eukaryotic chromatin domains. Here, we report that the extent of H4 acetylation within euchromatin and heterochromatic domains is linked with DNA replication rather than with transcriptional activity, whereas H3 acetylation remains fairly constant throughout the cell cycle.

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