Section 4
Chapter 3,472

In vitro activities of terbinafine against Aspergillus species in comparison with those of itraconazole and amphotericin B

Moore, C.B.; Walls, C.M.; Denning, D.W.

Antimicrobial Agents and ChemoTherapy 45(6): 1882-1885


ISSN/ISBN: 0066-4804
PMID: 11353643
DOI: 10.1128/aac.45.6.1882-1885.2001
Accession: 003471863

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Compared with the in vitro activities of itraconazole (geometric mean MIC (GM), 0.56 micro g/ml) and amphotericin B (GM, 0.66 micro g/ml), the in vitro activity of terbinafine was inferior against A. fumigatus (GM, 19.03 micro g/ml) (P<0.05) and superior against A. flavus (GM, 0.10 micro g/ml), A. terreus (GM, 0.16 micro g/ml), and A. niger (GM, 0.19 micro g/ml).

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