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Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight

Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight

Brain Research 848(1/2): 114-123

A review. Insulin and leptin are hypothesized to be 'adiposity signals' for the long-term regulation of body weight by the brain. Accordingly, a change in the plasma levels of leptin or insulin indicates a state of altered energy homeostasis and adiposity, and the brain responds by adjusting food intake to restore adipose tissue mass to a regulated level.

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Accession: 003480026

Download citation: RISBibTeXText

PMID: 10612703

DOI: 10.1016/s0006-8993(99)01974-5

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