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Insulin-like growth factor binding proteins and mitogenic activity of partially fractionated sheep amniotic fluid

Insulin-like growth factor binding proteins and mitogenic activity of partially fractionated sheep amniotic fluid

Acta Veterinaria Hungarica 49(1): 65-70

Amniotic fluid collected from 3 ewes on various days of gestation was examined for the presence of insulin-like growth factor (IGF) binding proteins. IGF-binding proteins with a molecular mass of 40-45 kDa appeared at day 41 of gestation. The level of these major IGF-binding proteins increased during pregnancy and reached a maximum at day 106. Smaller IGF-binding molecules with an approximate molecular mass of 35 kDa and 25 kDa appeared at day 90, also reaching a concentration peak at day 106.

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Accession: 003480071

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PMID: 11402691

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