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Intensive intravenous amphotericin B for prophylaxis of systemic fungal infections. Results of a prospective controlled pilot in acute leukemia patients



Intensive intravenous amphotericin B for prophylaxis of systemic fungal infections. Results of a prospective controlled pilot in acute leukemia patients



Chemotherapy Basel 46(4): 293-302



In a prospective pilot trial in Germany during May-December 1997 the safety and efficacy of antifungal prophylaxis with intravenous (i.v.) amphotericin B (AMB; 1 mg/kg every 48 h) was studied in 46 consecutive cycles. Prophylaxis with i.v. AMB was carried out in patients treated with intensive chemotherapy for acute leukaemia (AL) and compared with a control of 49 cycles without prophylaxis.

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Accession: 003480762

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DOI: 10.1159/000007301


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