+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Inter- and intra-species extrapolation in risk assessment of different classes of pesticides

Inter- and intra-species extrapolation in risk assessment of different classes of pesticides

Human and Ecological Risk Assessment 5(5): 985-996

Risk assessors routinely use the reference dose (RfD) approach for non- cancer risk assessment. In this approach, No-Observed-Adverse-Effect-Level (NOAEL) is divided by the product of uncertainty factors (UFs) and, occasionally, an additional modifying factor (MF), each usually employed by default as factors of 10.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 003480796

Download citation: RISBibTeXText

DOI: 10.1080/10807039991289275

Related references

CYP2E1 expression in bone marrow and its intra- and interspecies variability: Approaches for a more reliable extrapolation from one species to another in the risk assessment of chemicals. Archives of Toxicology 73(12): 618-624, 2000

Vinyl chloride mechanistic data and risk assessment: DNA reactivity and cross-species quantitative risk extrapolation. Pharmacology & Therapeutics 71(1-2): 7-28, 1996

Quantitative cross-species extrapolation in noncancer risk assessment. Regulatory Toxicology and Pharmacology 34(1): 62-68, 2001

Are current species extrapolation models a good basis for ecological risk assessment?. Environmental Toxicology and Chemistry ruary; 20(2): 442-447, 2001

Issues in biochemical applications to risk assessment: can in vitro studies assist us in species extrapolation?. Environmental Health Perspectives 76: 181-184, 1987

Inter-compartmental transport of organophosphate and pyrethroid pesticides in South China: implications for a regional risk assessment. Environmental Pollution 190: 19-26, 2014

In vivo tissue dosimetry as a basis for cross-species extrapolation in cancer risk assessment of propylene oxide. Regulatory Toxicology & Pharmacology. 20(1 Part 1): 1-14, 1994

Problems and prospects in inter species extrapolation. Roloff, M V (Ed ) Human Risk Assessment: The Role Of Animal Selection And Extrapolation; Symposium, St Louis, Missouri, Usa, October 28-31, 1985 Xvi+281p Taylor And Francis: Philadelphia, Pennsylvania, Usa; London, England, Uk Illus 253-266, 1987

Determination of inter- and intra-species genetic relationships among six Eucalyptus species based on inter-simple sequence repeats (ISSR). Tree Physiology 25(10): 1295-1302, 2005

Assessment of inter- and intra-specific variability in the main species of Boletus edulis complex by ITS analysis. Fems Microbiology Letters 243(2): 411-416, 2005

Intra-species, inter-species and inter-genera ovarian transfer and their spawning response. Marathwada Univ J Sci (Biol Sci): 136: 195-201, 1974

Inter-species extrapolation of pharmacokinetic data of three prostacyclin-mimetics. Prostaglandins. 48(5): 297-312, 1994

Oral-to-inhalation route extrapolation in occupational health risk assessment: a critical assessment. Regulatory Toxicology and Pharmacology 39(1): 5-11, 2004

Comparison of susceptibilities of species used in toxicological and environmental risk assessment to chemicals (pesticides). Archives of Toxicology. Supplement. 17: 434-445, 1995