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Invasive aspergillosis associated with prolonged leukopenia in a murine model



Invasive aspergillosis associated with prolonged leukopenia in a murine model



Journal de Mycologie Medicale 9(4): 221-225



A model of murine invasive pulmonary aspergillosis occurring after intranasal instillation of A. fumigatus conidia in mice receiving repeated injections of cyclophosphamide is described. The progressive dissemination of the fungus from lungs was followed in order to evaluate the extension of lesions inside the pulmonary tissue and to deep organs including kidney and brain.

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Accession: 003482915

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