Section 4
Chapter 3,488

Lactoferrin and eosinophilic cationic protein in nasal secretions of patients with experimental rhinovirus colds, natural colds, and presumed acute community-acquired bacterial sinusitis

Niehaus, M.D.; Gwaltney, J.M.; Hendley, J.O.; Newman, M.J.; Heymann, P.W.; Rakes, G.P.; Platts-Mills, T.A.; Guerrant, R.L.

Journal of Clinical Microbiology 38(8): 3100-3102


ISSN/ISBN: 0095-1137
PMID: 10921988
Accession: 003487673

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To distinguish sinusitis from uncomplicated "colds," we examined lactoferrin and eosinophilic cationic protein (ECP) in nasal secretions obtained from 9 healthy adults, 9 adults with natural colds and 16 adults with sinusitis in USA Nasal washings from 32 previously healthy volunteers exposed to an experimental rhinovirus were also examined. Lactoferrin titres were >=1:400 in 4% of persons with uncomplicated colds and controls but in 79% of persons with sinusitis or purulent sputa.

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