Memory in viral quasispecies
Ruiz-Jarabo, C.M.; Arias, A.; Baranowski, E.; Escarmís, C.; Domingo, E.
Journal of Virology 74(8): 3543-3547
ISSN/ISBN: 0022-538X PMID: 10729128 DOI: 10.1128/jvi.74.8.3543-3547.2000
In this study, we provide direct evidence that evolving viral quasi-species possess a molecular memory in the form of minority components that populate their mutant spectra. The experiments have involved foot-and-mouth disease virus populations with known evolutionary histories.