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Chapter 3,498

Memory in viral quasispecies

Ruiz-Jarabo, C.M.; Arias, A.; Baranowski, E.; Escarmís, C.; Domingo, E.

Journal of Virology 74(8): 3543-3547

2000


ISSN/ISBN: 0022-538X
PMID: 10729128
DOI: 10.1128/jvi.74.8.3543-3547.2000
Accession: 003497130

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In this study, we provide direct evidence that evolving viral quasi-species possess a molecular memory in the form of minority components that populate their mutant spectra. The experiments have involved foot-and-mouth disease virus populations with known evolutionary histories.

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