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Protection studies on winter dysentery caused by bovine coronavirus in cattle using antigens prepared from infected cell lysates



Protection studies on winter dysentery caused by bovine coronavirus in cattle using antigens prepared from infected cell lysates



Canadian Journal of Veterinary Research 64(2): 138-140



Cells infected with bovine coronavirus (BCV) were solubilized with Triton X-100 to yield a cell lysate (CL) antigen having high haemagglutinating (HA) titres. The antigen gave high HA titres using rat erythrocytes, suggesting that it contained large amounts of haemagglutinin esterase (HE) antigen. The CL antigen, combined with an oil adjuvant, was tested for protective and antibody-inducing activities in cattle.

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Accession: 003537028

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PMID: 10805255


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