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Protective immunity of DNA vaccine encoding Schistosoma japonicum Chinese strain triose-phosphate isomerase in infected BALB/c mice


Protective immunity of DNA vaccine encoding Schistosoma japonicum Chinese strain triose-phosphate isomerase in infected BALB/c mice



Chinese Journal of Parasitic Disease Control 14(3): 207-209



A study was conducted to develop SjCTPI DNA vaccine for Schistosoma japonicum infection. 39 BALB/c mice were divided into 3 groups. Group A mice (control group) were injected intramuscularly with 100 micro g of pcDNA3.1; group B mice (experimental group) were injected with 100 micro g of pcDNA3.1-SjCTPI; and group C mice (strengthened group) were injected with 100 micro g of pcDNA3.1-SjCTPI and 100 micro g of mixture of pcDNA3.1-P35 and pcDNA3.1-P40.

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