Staphylococcus aureus capsular polysaccharide type 5 conjugate and whole cell vaccines stimulate antibody responses in cattle
Tollersrud, T.; Zernichow, L.; Andersen, S.R.; Kenny, K.; Lund, A.
Vaccine 19(28-29): 3896-3903
ISSN/ISBN: 0264-410X PMID: 11427263 DOI: 10.1016/s0264-410x(01)00124-4
Dairy heifers were immunized subcutaneously with one of 4 different vaccines which contained preparations of Staphylococcus aureus capsular polysaccharide type 5 (CP5) and a mineral oil adjuvant, or received a placebo containing saline and adjuvant. The vaccine containing a CP5-human serum albumin conjugate (CP5-HSA) and the vaccine with formaldehyde inactivated whole cells expressing CP5, both elicited strong anti-CP5 antibody responses.