EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The efficacy of levamisole, and a mixture of oxfendazole and levamisole, against the arrested stages of benzimidazole-resistant Haemonchus contortus and Ostertagia circumcincta in sheep


Veterinary Parasitology 88(1/2): 139-146
The efficacy of levamisole, and a mixture of oxfendazole and levamisole, against the arrested stages of benzimidazole-resistant Haemonchus contortus and Ostertagia circumcincta in sheep
Sheep were allowed to graze pasture that had been seeded with benzimidazole-resistant Haemonchus contortus and Ostertagia circumcincta in order to acquire a burden of arrested larvae. Following housing, sheep were dosed orally with either oxfendazole at a dose rate of 4.7 mg/kg (to confirm the benzimidazole-resistant status of the species of nematode), levamisole at a dose rate of 7.5 mg/kg, or an oxfendazole/levamisole mixture at a dose rate of 4.6 mg/kg oxfendazole and 8.1 mg/kg levamisole. The efficacies of the treatments were assessed by estimation of the arrested larval burden in the abomasum of each sheep, either at 10 or 11 days (oxfendazole and oxfendazole/levamisole mixture), or 12 or 13 days (levamisole), after treatment. Compared to the untreated controls, the protection afforded by a single dose of either levamisole or the oxfendazole/levamisole mixture was >99% against the arrested stages of both Haemonchus contortus and Ostertagia circumcincta. Treatment with oxfendazole confirmed the benzimidazole-resistance status of the two species.

Accession: 003586414

PMID: 10681032

DOI: 10.1016/s0304-4017(99)00195-8

Download PDF Full Text: The efficacy of levamisole, and a mixture of oxfendazole and levamisole, against the arrested stages of benzimidazole-resistant Haemonchus contortus and Ostertagia circumcincta in sheep



Related references

The efficacy of levamisole, and a mixture of oxfendazole and levamisole, against the arrested stages of benzimidazole-resistant Haemonchus contortus and Ostertagia circumcincta in sheep. Veterinary Parasitology 88(1-2): 139-146, 2000

Comparison of six in vitro tests in determining benzimidazole and levamisole resistance in Haemonchus contortus and Ostertagia circumcincta of sheep. Veterinary Parasitology 80(3): 239-249, 1999

Comparison of six in vitro tests in determining benzimidazole and levamisole resistance in Haemonchus contortus and Ostertagia circumcincta of sheep. Veterinary Parasitology 80(3): 239-249, 1999

Removal of Haemonchus contortus, Ostertagia circumcincta and Trichostrongylus spp. from goats, by morantel citrate, levamisole hydrochloride, fenbendazole, and oxfendazole. New Zealand Veterinary Journal 35(12): 208-210, 1987

Haemonchus contortus and Ostertagia circumcincta resistant to levamisole. Revista do Centro de Ciencias Rurais 9(1): 101-102, 1979

Changes of ED-50 in in vitro egg hatch assays for detection of benzimidazole and levamisole resistance of Haemonchus contortus and Ostertagia circumcincta in lambs. Helminthologia (Bratislava) 32(4): 219-223, 1995

Efficacy of levamisole and closantel against benzimidazole resistant Haemonchus contortus of sheep. Indian Journal of Small Ruminants 9(2): 179-180, 2003

Efficiency of oxfendazole administered as a single dose or in a controlled release capsule against benzimidazole-resistant haemonchus contortus, Ostertagia circumcincta and Trichostrongylus colubriformis. Research in Veterinary Science 31(3): 289-294, 1981

Comparative efficacies of closantel, ivermectin, oxfendazole, thiophanate and levamisole against thiabendazole resistant Haemonchus contortus in sheep. Tropical Animal Health and Production 28(3): 216-220, 1996

Pharmacokinetic behaviour and anthelmintic efficacy of 1-n-butyl carbamoyl oxfendazole given by intramuscular injection Sheep, Trichostrongylus colubriformis, Haemonchus contortus and Ostertagia circumcincta. Veterinary research communications 6(3): 177-187, 1983