Allele frequencies of the PrP gene in 29 French sheep Breeds. Possible use in selection for resistance to scrapie
Palhiere, I.; Francois, D.; Elsen, J.M.; Barillet, F.; Amigues, Y.; Perret, G.; Bouix, J.
Proceedings of the 7th World Congress on Genetics Applied to Livestock Production, Montpellier, France, August, 2002 Session 13: 1-4
2002
Accession: 003637560
Genetic variability of susceptibility to transmissible spongiform encephalopathies of small ruminants is mainly explained by the polymorphism of the PrP gene. A survey was conducted in France in order to estimate the initial frequencies of four PrP alleles related to resistance (ARR allele) or increasing levels of susceptibility to scrapie (AHQ, ARQ and VRQ alleles). Representative samples of about 100 animals in 29 sheep breeds were genotyped.
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Isabelle Palhiere; Mickaël Brochard; Katayoun Moazami-Goudarzi; Denis Laloë; Yves Amigues; Bertrand Bed'hom; Étienne Neuts; Cyril Leymarie; Thais Pantano; Edmond Paul Cribiu; Bernard Bibé; Étienne Verrier 2008: Impact of strong selection for thePrPmajor gene on genetic variability of four French sheep breeds (Open Access publication) Genetics Selection Evolution 40(6): 663-0