Section 4
Chapter 3,638

Allele frequencies of the PrP gene in 29 French sheep Breeds. Possible use in selection for resistance to scrapie

Palhiere, I.; Francois, D.; Elsen, J.M.; Barillet, F.; Amigues, Y.; Perret, G.; Bouix, J.

Proceedings of the 7th World Congress on Genetics Applied to Livestock Production, Montpellier, France, August, 2002 Session 13: 1-4


Accession: 003637560

Genetic variability of susceptibility to transmissible spongiform encephalopathies of small ruminants is mainly explained by the polymorphism of the PrP gene. A survey was conducted in France in order to estimate the initial frequencies of four PrP alleles related to resistance (ARR allele) or increasing levels of susceptibility to scrapie (AHQ, ARQ and VRQ alleles). Representative samples of about 100 animals in 29 sheep breeds were genotyped.

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