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Anthelmintic activity of Xanthium strumarium against Haemonchus contortus infection in sheep

Sharma, S.; Singh, D.; Khan, F.; Swarankar, C.; Bhagwan, P.

Indian Journal of Animal Sciences il; 73(4): 342-344

2003


Accession: 003645795

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Anthelmintic activity of the fresh juice of Xanthium strumarium leaves at different concentrations was evaluated in vitro, against benzimidazole resistant Haemonchus contortus strain, using egg hatch assay (EHA) and larval paralysis test (LPT). No anthelmintic activity of the Xanthium strumarium juice was observed at 1: 100 dilution, however, undiluted juice of the leaves showed a 100% inhibition in egg hatching by EHA. The inhibition in egg hatching was 100% at 1: 2 and 1: 10 dilutions of the juice, whereas at 1: 50 dilution, it was only 21.5%, after 48 hr of incubation.'The control mortality was 12.1%. In LPT, the percentage paralysis of the larvae at concentrations - undiluted, 1: 2, 1: 5, 1: 10 and 1: 100 were 23.8%, 25.5%, 21.5%, 17.7% and 5.44%, respectively, indicating significant (P<0.05) anthelmintic activity up to 1: 10 dilution of the juice. The per cent survivability of the larvae in the control group was 97.5.

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