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Antimycobacterial flavones from Haplopappus sonorensis



Antimycobacterial flavones from Haplopappus sonorensis



Fitoterapia 74(3): 226-230



Crude extracts of Haplopappus sonorensis (A. Gray) S.F. Blake (Asteraceae), showed activity against Mycobacterium tuberculosis H(37)Rv. By assay-guided fractionation, 5-hydroxy-3,7,4'-trimethoxyflavone (1). 5,7-dihydroxy-3,4'-dimethoxyflavone (2). and 5,4'-dihydroxy-3,7-dimethoxyflavone (3). were identified as the antimycobacterial principles. Compound 2 was the most active compound.

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Accession: 003647739

Download citation: RISBibTeXText

PMID: 12727485

DOI: 10.1016/s0367-326x(03)00033-9


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