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Clearing the way to implantation

Clearing the way to implantation

Journal of Clinical Investigation 109(2): 169-170

ISSN/ISBN: 0021-9738

PMID: 11805127

The role of a specific carbohydrate-binding protein, the mannose/GalNAc-4-SO<sub>4</sub> receptor (M/G4SR), in mammalian physiology, specifically in reproduction, was elucidated. An attempt was made to generate the relevant null mutant, but the resultant M/G4SR<sub>-/-</sub> homozygotes died in utero. Thus, attention was turned to the heterozygous state of the receptor gene (M/G4SR-/+).

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Accession: 003680058

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