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Clenbuterol in the horse: confirmation and quantitation of serum clenbuterol by LC-MS-MS after oral and intratracheal administration


Clenbuterol in the horse: confirmation and quantitation of serum clenbuterol by LC-MS-MS after oral and intratracheal administration



Journal of Analytical Toxicology 25(4): 280-287



ISSN/ISBN: 0146-4760

PMID: 11386642

DOI: 10.1093/jat/25.4.280

Clenbuterol is a beta 2 agonist/antagonist bronchodilator, and its identification in post-race samples may lead to sanctions. The objective of this study was to develop a specific and highly sensitive serum quantitation method for clenbuterol that would allow effective regulatory control of this agent in horses. Clenbuterol-d9 was synthesized for use as an internal standard. An automated solid-phase extraction method was developed.

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Accession: 003680078

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