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Cloning and sequence analysis of translational release factors eRF1 and eRF3 of Pneumocystis carinii


Cloning and sequence analysis of translational release factors eRF1 and eRF3 of Pneumocystis carinii



Journal of Eukaryotic Microbiology Suppl: 116s-117s



ISSN/ISBN: 1066-5234

PMID: 11906017

The complementary DNA and genomic sequences for eRF1 and eRF3 from rat P. carinii were cloned and analysed. P. carinii eRF1 (Pc-eRF1) is composed of 432 amino acids and shares 80% and 78% sequence homology with Saccharomyces cerevisiae eRF1 and S. pombe eRF1, respectively. The deduced P. carinii eRF3 (Pc-eRF3) structure is composed of an N-terminal non-conservative sequence (which shares no homology with any known eRF3 sequences) and a C-terminal conservative sequence.

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Accession: 003681556

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