+ Translate
+ Most Popular
Investigations on the organic drift in North Swedish streams
Limitations of Using Microsoft Excel Version 2016 (MS Excel 2016) for Statistical Analysis for Medical Research
Phloem necrosis of coffee in Surinam
Anatomy of Mystus seenghala IV Nervous system
Integrated farming system for gardenland conditions of Coimbatore district - an over view
Tetrapleure (Tetrapleura tetraptera), an unknown African medicinal and spice plant
The origin and phylogenetic significance of the trochophoran larvae 2. evolutionary significance of the larvae of coelomate worms and mollusks
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
Enterobacter amnigenus. An unusual human pathogen
Influence of Seriboost foliar application on leaf yield and leaf protein content in mulberry (Morus spp.), in relation to silkworm cocoon production
The identity of the lipstick mold of cultivated mushrooms agaricus bisporus
Advantages and disadvantages of bordeaux mixture and of lime-sulphur used on apples in the growing season
'Pan-sukh' disease of Rice in the Central Provinces
Geological age of the Ptilophyllum flora; a critical reassessment
Study of vitellogenesis in birds; physiological phases & role of folliculin in vitellogenesis
Evaluation of WCT coconut and Komadan coconut
Therapy for acne with saccharomyces boulardii
Evidence for Late Cretaceous N-S dextral shear in the west-central crystalline core, North Cascades, Washington
'Rajeshwari' - a high-yielding white seeded variety of sesame for Andhra Pradesh
Manufacture of Ricotta cheese from whey fortified with skim milk powder using different acidulants
Occurrence of Eutrichophilus mexicanus (Rudow, 1866) and Eutrichophilus lobatus (Ewing, 1936) (Phthiraptera: Trichodectidae) on Sphiggurus villosus (Cuvier, 1825) (Rodentia: Erethizontidae) in Rio de
Factors affecting fruitfulness in durian (Durio zibethinus Murr.). I. Flowering and pollination
Bronchial cuff pressure change caused by left-sided double-lumen endobronchial tube displacement
Some Biological Applications of Organometallic Compounds
The composition of pampas-grass (Cortaderia argentea.)

Cognitive effects of endocrine-disrupting chemicals in animals

Cognitive effects of endocrine-disrupting chemicals in animals

Environmental Health Perspectives 109(12): 1197-1206

ISSN/ISBN: 0091-6765

PMID: 11748026

DOI: 10.2307/3454741

A large number of chemical pollutants including phthalates, alkylphenolic compounds, polychlorinated biphenyls and polychlorinated dibenzodioxins, organochlorine pesticides, bisphenol A, and metals including lead, mercury, and cadmium have the ability to disrupt endocrine function in animals. Some of these same chemicals have been shown to alter cognitive function in animals and humans. Because hormonally mediated events play a central role in central nervous system development and function, a number of researchers have speculated that the changes in cognitive function are mediated by the endocrine-like actions of these chemicals. In this paper we review the evidence that cognitive effects of chemicals classified as environmental endocrine disruptors are mediated by changes in hormonal function. We begin by briefly reviewing the role of gonadal steroids, thyroid hormones, and glucocorticoids in brain development and brain function. We then review the endocrine changes and cognitive effects that have been reported for selected endocrine-disrupting chemicals, discuss the evidence for causal relationships between endocrine disruption and cognitive effects, and suggest directions for future research.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 003682640

Download citation: RISBibTeXText

Related references

Effects of endocrine disrupting chemicals on aquatic organisms Environmental endocrine disruptors. Nippon Suisan Gakkaishi 64(5): 899-900, 1998

Epigenetic Modifications due to Environment, Ageing, Nutrition, and Endocrine Disrupting Chemicals and Their Effects on the Endocrine System. International Journal of Endocrinology 2020: 9251980, 2020

Statement from the work session on environmental endocrine-disrupting chemicals: neural, endocrine, and behavioral effects. Toxicology and industrial health 14(1-2): 1-8, 1998

Endocrine potency of wastewater: contents of endocrine disrupting chemicals and effects measured by in vivo and in vitro assays. Environmental Toxicology and Chemistry 30(2): 413-426, 2011

Endocrine Disrupting Chemicals: Effects on Endocrine Glands. Frontiers in Endocrinology 10: 178, 2019

Effects of perinatal exposure of five putative endocrine disrupting chemicals , methoxychlor, genistein, diisononylphthalate 4-nonylphenol and bisphenol A, on endocrine/reproductive systems in rats. Toxicological Sciences 72(S-1): 77, 2003

Disruption by stealth - Interference of endocrine disrupting chemicals on hormonal crosstalk with thyroid axis function in humans and other animals. Environmental Research 2021: 111906, 2021

Endocrine-disrupting chemicals and their effects on puberty. Best Practice and Research. Clinical Endocrinology and Metabolism 2021: 101579, 2021

Effects of endocrine disrupting chemicals on amphibians. American Zoologist 38(5): 177A, 1998

Effects of Endocrine-Disrupting Chemicals on the Ovary. Biology of Reproduction 93(1): 20, 2015

The effects of endocrine disrupting chemicals on the ovary. Frontiers in Bioscience: a Journal and Virtual Library 7: D1941-D1948, 2002

Thyroid effects of endocrine disrupting chemicals. Molecular and Cellular Endocrinology 355(2): 240-248, 2012

Effects of endocrine disrupting chemicals in pigs. Environmental Pollution 263(Pt B): 114505, 2020

Immunomodulatory effects of environmental endocrine disrupting chemicals. Kaohsiung Journal of Medical Sciences 28(7 Suppl): S37-S42, 2012

Effects of endocrine-disrupting chemicals on adrenal function. Best Practice and Research. Clinical Endocrinology and Metabolism 20(1): 111-120, 2006