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Combined treatment of Tourette syndrome with Delta 9-THC and dopamine receptor antagonists


Combined treatment of Tourette syndrome with Delta 9-THC and dopamine receptor antagonists



Journal of Cannabis Therapeutics 2(3/4): 145-154



Animal studies suggest that cannabinoid receptor agonists might enhance the effect of dopamine receptor antagonists (neuroleptics, NL) in hyperkinetic movement disorders. In Tourette syndrome, NL are the most effective drugs for the treatment of tics. Recent clinical trials demonstrated that delta-9-tetrahydrocannabinol ( Delta 9-THC) also produces a tic-suppressing effect.

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