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Combined treatment of Tourette syndrome with Delta 9-THC and dopamine receptor antagonists

Combined treatment of Tourette syndrome with Delta 9-THC and dopamine receptor antagonists

Journal of Cannabis Therapeutics 2(3/4): 145-154

Animal studies suggest that cannabinoid receptor agonists might enhance the effect of dopamine receptor antagonists (neuroleptics, NL) in hyperkinetic movement disorders. In Tourette syndrome, NL are the most effective drugs for the treatment of tics. Recent clinical trials demonstrated that delta-9-tetrahydrocannabinol ( Delta 9-THC) also produces a tic-suppressing effect.

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