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Comparative pharmacokinetics of metronidazole in camels, sheep and goats

Comparative pharmacokinetics of metronidazole in camels, sheep and goats

Acta Veterinaria Brno 72(1): 49-53

ISSN/ISBN: 0001-7213

The pharmacokinetics of metronidazole were determined after a single intramuscular (i.m.) dose of 30 weight in five camels, sheep and goats. Marked differences were found between the three species in some of the kinetic parameters. For example, the elimination half-lives (t1/2; h) in camels, sheep and goats were 10.0, 6.21 and 5.87, respectively. The drug maximum concentrations in plasma, Cmax (, were 28.3, 54.6 and 54.4 in camels, sheep and goats, respectively.

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