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Comparative reactivity of human sera to recombinant VlsE and other Borrelia burgdorferi antigens in class-specific enzyme-linked immunosorbent assays for Lyme borreliosis


Comparative reactivity of human sera to recombinant VlsE and other Borrelia burgdorferi antigens in class-specific enzyme-linked immunosorbent assays for Lyme borreliosis



Journal of Medical Microbiology 51(8): 649-655



ISSN/ISBN: 0022-2615

PMID: 12171295

A comparative study of human sera was conducted to determine which purified preparations of 11 recombinant antigens of Borrelia burgdorferi sensu stricto were diagnostically most important in ELISAs. To assess sensitivity, 20 serum samples obtained 1-6 weeks after onset of illness from 20 persons, in the USA, who had physician-diagnosed erythema migrans (EM) were tested for IgM and IgG antibodies.

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Accession: 003685671

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