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Comparison of hamster and pony challenge models for evaluation of effect of antigenic drift on cross protection afforded by equine influenza vaccines


Comparison of hamster and pony challenge models for evaluation of effect of antigenic drift on cross protection afforded by equine influenza vaccines



Equine Veterinary Journal 35(5): 458-462



ISSN/ISBN: 0425-1644

PMID: 12875323

DOI: 10.2746/042516403775600433

Reasons for performing study: Vaccination and challenge studies in ponies are the most relevant experimental system for predicting whether strains included in equine influenza vaccines are relevant, but they are difficult to perform. Objectives: In order to investigate the feasibility of using a small animal model, results of a cross-protection study in hamsters were compared with those from a previous pony challenge experiment.

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Accession: 003687506

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