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Comparison of in vitro activities of gatifloxacin and ciprofloxacin against four taxa of rapidly growing mycobacteria



Comparison of in vitro activities of gatifloxacin and ciprofloxacin against four taxa of rapidly growing mycobacteria



Antimicrobial Agents and ChemoTherapy 46(10): 3283-3285



By using current NCCLS broth microdilution methods, we found that gatifloxacin inhibited 90% of Mycobacterium fortuitum group isolates (n=39) at <=0.12 micro g/ml, 90% of M. mucogenicum isolates (n=20) at <=0.25 micro g/ml, and 90% of M. chelonae isolates (n=32) at <=4 micro g/ml. Gatifloxacin can only inhibit 90% M. abscessus isolates (n=24) at >32 micro g/ml. Gatifloxacin was generally fourfold more active than ciprofloxacin.

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Accession: 003687556

Download citation: RISBibTeXText

PMID: 12234861

DOI: 10.1128/aac.46.10.3283-3285.2002


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